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The 3,000-mile Mekong River runs throughout Asia and affords an experience of the continent like no other.



Sa Đéc is a Provincial city in Đồng Tháp Province in the Mekong Delta of southern Vietnam. It is a river port and agricultural and industrial trading center. The Sa Đéc economic zone consists of Châu Thành, Lai Vung and Lấp Vò districts. As of January 2018, the city has a population of approximately 202,046

Tân Châu is a town of An Giang Province in the Mekong Delta region of Vietnam. As of 2009 the town had a population of 184,129. The town covers an area of 175.68 km². It is famous for Tân Châu silk with the famous product Lãnh Mỹ A, whose black colour comes from the Diospyros mollis's fruit.



On the banks of the Mekong, the capital of Cambodia dares to dazzle from the moment you set foot on shore.


On the banks of the Mekong, the capital of Cambodia dares to dazzle from the moment you set foot on shore.

Oudong is a town in Cambodia, at the base of Phnom Udong Mountain, northwest of Phnom Penh. It was the site of the royal capital from the 17th to the 19th centuries. The mountain’s 2 mounds are connected by a ridge and dotted with stupas and shrines dedicated to former kings. Chedi Mouk Pruhm is the burial site of King Monivong. The ruins of Arthross Temple house a large golden Buddha.

Koh Chen Cambodia. The small village of Koh Chen lies on the Tonle River close to Oudong


Angkor Ban is a khum of Sampov Loun District in Battambang Province in north-western Cambodia





The 3,000-mile Mekong River runs throughout Asia and affords an experience of the continent like no other.
Beginning with a two-night stay in vibrant Ho Chi Minh City, you'll explore the city's fascinating history, including a speedboat excursion to the legendary Cu Chi Tunnels, while enjoying exclusive dining experiences and the opportunity to delve deeper into local life through sightseeing, cooking classes or Tai Chi.
The adventure continues aboard the elegant Mekong Serenity, where you'll embark on a seven-night all-inclusive cruise along the iconic Mekong River. Sailing through Vietnam and into Cambodia, you'll visit charming riverside towns and villages including Cai Be, Sa Dec and Tan Chau, discovering colourful markets, colonial architecture, traditional workshops and authentic local culture. With all sightseeing excursions included, you'll gain a unique insight into daily life along one of Asia's most fascinating waterways.




In Cambodia, the journey reveals a rich tapestry of history and heritage. Explore Phnom Penh's grand landmarks, visit poignant sites such as the Killing Fields and Tuol Sleng Genocide Museum, or enjoy alternative experiences including cyclo tours and local brewery visits. Further highlights include a Buddhist blessing at a local monastery, visits to traditional villages, and authentic encounters with local communities that showcase Cambodia's enduring traditions and warm hospitality.
The holiday concludes with a three-night stay in Siem Reap, home to the magnificent temples of Angkor. Witness an unforgettable sunrise over Angkor Wat, explore the UNESCO-listed Angkor Archaeological Park, and choose from a selection of cultural and countryside experiences. Combining luxury accommodation, carefully curated excursions, flights, transfers, drinks, Wi-Fi and gratuities, included on the cruise, this exceptional APT Touring itinerary provides a comprehensive introduction to two of Southeast Asia's most enchanting destinations.
2027 All-Inclusive 5★ Vietnam & Cambodia Highlights Sale
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Per-Person Pricing
* Prices shown are per person, based on two adults sharing a twin cabin and include all cruise offer discounts and savings.
| Deck | Price | Enquire | |
| A | Orchid Deck | Enquire now |
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| B | Orchid Deck | Enquire now |
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| C | Lily Deck | Enquire now |
| Deck | Price | Enquire | |
| D | Lily Deck | Enquire now |
| Deck | Price | Enquire | |
| ANG | Lotus Deck | Enquire now |
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| BAY | Lotus Deck | Enquire now |
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| E | Lily Deck | Enquire now |
Launched as part of APT Cruising’s fleet, Mekong Serenity offers an elegant and immersive way to explore the iconic Mekong River. Designed to accommodate fewer guests, the ship offers a relaxed, intimate atmosphere, allowing travellers to enjoy the journey at an unhurried pace while experiencing the cultures and landscapes of Southeast Asia. On board, spacious balcony suites, refined dining venues and welcoming social areas create a comfortable base between excursions. Large windows and open decks ensure the ever-changing scenery of the Mekong is always in view, whether you’re relaxing with a drink in the lounge or enjoying a quiet moment on deck. Sailing between Vietnam and Cambodia, Mekong Serenity journeys through vibrant cities, traditional villages and lush river landscapes.
What’s onboard: 88 guests, 44 guest staterooms, one speciality restaurant, two complimentary restaurants, two bars and lounges, two relaxation and fitness venues and one essential venue.
Booking conditions of APT Group and Reader Offers Limited Agency terms of business apply. Fares are per person based on two adults sharing, except single cabins and may increase or be withdrawn at any time. Offer applies to new bookings only. Savings are based on two adults sharing. Regional flights will incur supplementary costs and may require an additional overnight stay. Drink inclusions are subject to the cruise lines t&c's. Tours are subject to change, are non-transferable and may not be suitable for guests with mobility restrictions. Please note, walking tours are weather dependent. Please note, itinerary is subject to change due to water levels and other uncontrollable factors. Named hotels are subject to change. Meals are included as stated B=Breakfast L=Lunch D=Dinner. 5 star refers to the cruise element only. All-inclusive refers to the cruise element only. Savings are based on per cabin total. Cruise Miles T&Cs apply. E&OE
Agent to ABTA & ATOL holder APT (V9080/6781)
John Lewis Gift Card is based on one per booking, for UK mainland addresses only when booking an Oceanview or above by 8pm 10th November 2026. The amount is tiered on cabin grade booked.
View ROL Cruise Payment Methods HERE (these are not valid on holidays within the balance due date)